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Durogesic Patches when applied to the body last for Three Days. when replacing the patch it must be placed in a different place than the last one, this is to ensure the skin does not become so soft that is tears. Durogesic or D-TRAND Patches tend to melt the skin like Acid would. they make the skin very soft and they should not be applied while the Pores are open as Overdose is a very real option, Durogesic is approx 1000 times more potent than Morphine it was discovered in 1958 by Dr Paul Janson and is a Powerful Synthethic Opiod IT is supplied im MICROGRAMS rather than Miligrams as it is so strong, generally Prescribed for Cancer sufferers you really cannot get a more powerfull Painkiller. as a matter of interest during the Beslam Siege in Russia a few years ago, the russian special forces or SPETSNAS pumped the drug in its Gaseous form in the air vents to knock the Terrorists out unfortunally it killed a lot of the captives by Slowing down thier breathing untill they died, it is very toxice so PLEASE DONT MESS WITH IT, I hope this answers your Question,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,

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