answersLogoWhite

0

What does Cyclooxygenase 1 do?

Updated: 9/20/2023
User Avatar

GaleEncyofSurgery

Lvl 1
13y ago

Best Answer

Cyclooxygenase 1 is important for homeostatic maintenance such as platelet aggregation, the regulation of blood flow in the kidney and stomach, and the regulation of gastric acid secretion

User Avatar

Wiki User

13y ago
This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: What does Cyclooxygenase 1 do?
Write your answer...
Submit
Still have questions?
magnify glass
imp
Related questions

Where can one find information about Cyclooxygenase?

Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the past decade, however, more progress has been made in understanding the role of cyclooxygenase enzymes in biology and disease than at any other time in history. Two cyclooxygenase isoforms have been identified and are referred to as COX-1 and COX-2. Under many circumstances the COX-1 enzyme is produced constitutively (i.e., gastric mucosa) whereas COX-2 is inducible (i.e., sites of inflammation). Here, we summarize the current understanding of the role of cyclooxygenase-1 and -2 in different physiological situations and disease processes ranging from inflammation to cancer.


Which drugs blocks the cyclooxygenase pathway in platelets?

aspirin


What is the enzyme classification of cyclooxygenase?

oxidoreductase ,transferase ,hydrolases, lyases ,isomerases and ligases.


What is a Cox-2 inhibitor?

Cox-2 inhibitors are non-steroidal anti-inflammatory drugs (NSAIDs) which selectively inhibit cyclooxygenase-2.


What is a cox?

The word cox is short for coxswain, the helmsman of a boat, especially of a racing crew.It is also an abbreviation for cyclooxygenase, an enzyme group active in the stomach and kidneys.


Do platelets have nucleus?

No, platelets are cell fragments. They do not have a nucleus.


What role does cyclooxygenase play in pain and inflammation?

There are two types of Cox, theres Cox-1 and Cox-2. Cox-1 is an enzyme that helps regulate stomach acid and keep it in the stomach. While Cox-2 promotes inflammationin the body, now this is neccesarily a bad thing. Unless There becomes a high amount of Cox-2.


What is a prostaglandin hormone made from?

They are synthesized in the cell from the essential fatty acids (EFAs). An intermediate arachidonic acid is created from diacylglycerol via phospholipase-A2, then brought to either the cyclooxygenase pathway or the lipoxygenase pathway to form either prostaglandin and thromboxane or leukotriene respectively. The cyclooxygenase pathway produces thromboxane, prostacyclin and prostaglandin D, E and F. Alternatively, the lipoxygenase enzyme pathway is active in leukocytes and in macrophages and synthesizes leukotrienes. Dr.Fabianski Benjamin


How does pain pills alliveate pain?

Common knowledge would tell you that all pain medications are the same, when in fact, there are several different classifications. Pain killers such as Acetaminophen and Iubprofen (which can be found over-the-counter) work by inhibiting an enzyme known as cyclooxygenase, this specific enzyme helps fatty acids reach a chemical in the body called prostaglandins (which produces pain, inflammation and fevers etc.) By blocking cyclooxygenase you therefore reduce the pain. Now, on the other hand, Narcotic pain killers like hydrocodone, oxycodone and morphine work by changing the way your body percieves pain. This type of medication is usually found in a combination that includes Acetaminophen or Iubprofen.


How does ibuprofen work?

Ibuprofen and ArthritisIbuprofin is a nonsteroidal anti-inflammatory drug (NSAID), like aspirin, that is used to reduce the inflammation that causes joint pain, stiffness, and swelling. Ibuprofen is in a class of drugs called Nonsteroidal AntiInflammatory Drugs (NSAIDS). The NSAID class includes aspirin, naprosyn (Alleve, and many others. Ibuprofen is a nonspecific cycloxygenase inhibitor. Cyclooxygenase is an enzyme that changes a specific fatty molecule (arachidonic acid) into other chemicals (prostaglandins) that cause inflammation. NSAIDS block this conversion and thereby decrease inflammation. Ibuprofen is nonspecific, blocking both of the two types of cyclooxygenase, called COX1 and and COX2. Because it blocks COX1, ibuprofen is damaging to the stomach, as is aspirin.More input from others:My GP prescribed 400mg every 6 hours before my appointment with a bone specialist. It greatly helped the burning pain I've been having. (The bone scan I was given showed that my back was inflamed. This has decreased greatly since taking the ibuprofin treatment.)


Is Asprin NSAID?

Yes it is, via Wikipedia: http://en.wikipedia.org/wiki/Asprin Aspirin is part of a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs), but differs from most other NSAIDS in the mechanism of action. Though it, and others in its group called the salicylates, have similar effects (antipyretic, anti-inflammatory, analgesic) to the other NSAIDs and inhibit the same enzyme cyclooxygenase, aspirin (but not the other salicylates) does so in an irreversible manner and, unlike others, affect more the COX-1 variant than the COX-2 variant of the enzyme.[12]


What is the difference between Vicodin and Vicodin ibuprofen?

Vicoden is an opiate, like heroin but at a lesser degree. It works by flooding the opioid receptors in your brain which causes a euphoric, pain free sensation. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that works by limiting the amount of cyclooxygenase (COX-2) your body produces, which relieves swelling and pain.