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Prime factor the 2.
45 = 9x5 = 3x3x5
81 = 9x9 = 3x3x3x3

Your LCM will contain all the multiples of both numbers. 45 has 2 threes and 1 five. 81 has 3 threes. Together you need 4 threes and 1 five to cover both numbers. Therefore your LCM = 3x3x3x3x5 = 405.

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Q: What is the Lowest Common Multiple of 45 and 81?
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