Of course! I'd be happy to help you with your Statistics homework and provide a step-by-step solution to enhance your understanding of the concepts. Here is the sample question with the solution.
Question:
A pharmaceutical company is conducting a study to evaluate the effectiveness of a new drug in reducing blood pressure. The company randomly selects 100 patients with hypertension and divides them into two groups: a treatment group receiving the new drug and a control group receiving a placebo. After 12 weeks, the systolic blood pressure measurements (mmHg) for each patient are recorded. The data collected for the treatment group are as follows:
Treatment Group (new drug):
Mean systolic blood pressure = 128
Standard deviation = 10
The data collected for the control group (placebo) are as follows:
Control Group (placebo):
Mean systolic blood pressure = 136
Standard deviation = 12
Using appropriate statistical techniques, determine whether there is a significant difference in the mean systolic blood pressure between the treatment and control groups. Assume a significance level of 0.05.
Solution:
To determine whether there is a significant difference in the mean systolic blood pressure between the treatment and control groups, we can perform an independent samples t-test.
Step 1: State the hypotheses:
Null hypothesis (H0): The mean systolic blood pressure in the treatment group is equal to the mean systolic blood pressure in the control group.
Alternative hypothesis (Ha): The mean systolic blood pressure in the treatment group is not equal to the mean systolic blood pressure in the control group.
Step 2: Set the significance level:
The significance level (α) is given as 0.05.
Step 3: Compute the test statistic:
We can use the two-sample independent t-test formula to calculate the test statistic:
t = (mean1 - mean2) / sqrt[(s1^2 / n1) + (s2^2 / n2)]
where:
mean1 = mean systolic blood pressure in the treatment group
mean2 = mean systolic blood pressure in the control group
s1 = standard deviation of systolic blood pressure in the treatment group
s2 = standard deviation of systolic blood pressure in the control group
n1 = sample size of the treatment group
n2 = sample size of the control group
Plugging in the given values, we have:
mean1 = 128, mean2 = 136, s1 = 10, s2 = 12, n1 = 100, n2 = 100
t = (128 - 136) / sqrt[(10^2 / 100) + (12^2 / 100)]
= -8 / sqrt[1 + 1.44]
= -8 / sqrt(2.44)
≈ -8 / 1.56
≈ -5.13
Step 4: Determine the critical value:
Since the test is a two-tailed test and the significance level is 0.05, we need to find the critical value corresponding to a significance level of 0.025 in each tail. From the t-distribution table or statistical software, the critical value for a two-tailed test with a degree of freedom (df) of 198 (n1 + n2 - 2) is approximately ±1.972.
Step 5: Make a decision:
Since the absolute value of the test statistic (-5.13) is greater than the critical value (1.972), we reject the null hypothesis.
Step 6: State the conclusion:
There is sufficient evidence to conclude that there is a significant difference in the mean systolic blood pressure between the treatment and control groups (p < 0.05). The new drug appears to have a significant effect on reducing blood pressure compared to the placebo.
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