The lowest term has already been reduced as far as it will go. It is not possible to reduce it further.
3/5
5/9
2
-2/5
2/5
1/2
if you mean 40/64 then it is 5/8 in its lowest terms
11/40 is in its lowest terms.
14/45 is already a fraction in its lowest terms.
4/9
10/30