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The easiest way is to look it up in a book! But if you mean how can you measure it directly, it really depends what you tools and information you give yourself to start with. How hard to you want to make it for yourself? Since it is a known number that is easily determined from other known quantities, it is a kind of artificial problem... which means that how you find it depends on what information you have. As I said, you can just look it up... in a book or on this site!

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16y ago
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Q: How do you determine avogadro's number?
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