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combining the 26 letters with the 10 digits you have 36 possible characters to choose from to go into 16 slots. Grab the nearest scientific calculator, or use Google or whatever you like, and use the permutation function nPr, inputting 36P16 you get 1.529x1023 different possible combinations to 4 significant figures.

Alternatively if you don't have the use of the nPr function you can use the formula n!/(n-r)! where n is the characters available and r is the amount of slots they have to go in.

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Q: How many combinations can you make with numbers 0-9 and using all the letters of the alphabet to make a 16 digit code. For example the code on the back of iTunes gift cards... Thanks?
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