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In an experiment usually variables are controlled except for the independent variable. This one variable is changed and the dependent variable is read or observed. It becomes very hard to determine the effect of the independent variable if two variables are allowed to change and dependent variable observed because there is no way of easily determining the effect of the independent variable.

When scientists are checking the impact of drugs or a social initiative on humans they will say "all other factors like age, gender, income etc have been eliminated/ adjusted/ controlled" except for this one factor ie the social initiative eg the effect on reading ability of teenagers of teaching children to know their letters before school age or the effect of marijuana use on income etc.

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