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Myelofibrosis goes by many names including idiopathic myelofibrosis, agnogenic myeloid metaplasia, chronic myelosclerosis, aleukemic megakaryocytic myelosis, and leukoerythroblastosis

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14y ago

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Is myelofibrosis easy to diagnose?

Because symptoms are similar to other diseases (mostly leukemias), myelofibrosis is not easy to diagnose


Can Myelofibrosis get worse?

Myelofibrosis can progress to acute lymphocytic leukemia or lymphoma


What does Myelofibrosis stem from?

Myelofibrosis is caused by an abnormality in a single stem cell, which causes it to grow out of control


Is idiopathic myelofibrosis fatal?

Idiopathic myelofibrosis typically becomes progressively worse and can cause death


Does myelofibrosis always produce symptoms?

About one quarter of all patients with myelofibrosis have no symptoms (asymptomatic)


Does chemotherapy cause myelofibrosis?

Chemotherapy can potentially contribute to the development of myelofibrosis, particularly as a late effect following treatment for certain cancers. It may cause damage to the bone marrow, leading to abnormal scar tissue formation and impaired blood cell production. However, myelofibrosis can also arise from other causes, including genetic mutations and underlying diseases. If you have concerns about chemotherapy and myelofibrosis, it’s important to discuss them with a healthcare professional.


Does Bone marrow transplantation treat myelofibrosis?

Although historically there has not been much improvement in the treatment of myelofibrosis, that has changed recently. The main treatment now consists of taking a medication known as "Jakafi" which targets the gene thought to cause myelofibrosis.


Is fatigue a symptom of myelofibrosis?

Yes


Is fever a symptom of myelofibrosis?

Yes


Is itchiness a symptom of myelofibrosis?

Yes


Is Myelofibrosis associated with leukoerythroblastosis?

Yes


Is Myelofibrosis associated with tuberculosis?

Yes