Concentric
lamellae.
Concrete lamellae
The layers of calcified matrix in bone tissue are called lamellae. These lamellae are arranged in concentric circles around central canals called Haversian canals, forming the structure known as an osteon or Haversian system.
former osteoblasts that have become surrounded in bone matrix that is calcified
The process that breaks down the calcified matrix is primarily carried out by cells called osteoclasts. These cells resorb bone tissue by dissolving the mineral components and degrading the organic matrix. Once the calcified matrix is broken down, it is replaced by bone-building cells known as osteoblasts, which synthesize new bone matrix and facilitate bone formation. This dynamic process is essential for bone remodeling and maintenance.
Rings of calcified matrix that make up the Haversian system are called lamellae. These concentric layers surround the central Haversian canal, which contains blood vessels and nerves. The arrangement of lamellae provides strength and structural support to bone tissue. Together, they facilitate the organized distribution of nutrients and waste removal within the bone.
Osteoporosis is a serious bone disease characterized by excessive loss of both calcified matrix and collagenous fibers, leading to weaker, more brittle bones that are at a higher risk of fractures. It is often associated with aging, hormonal changes, and nutritional deficiencies.
The matrix of the bone (calcified hydroxyapatite) is non-living; the living part of the bone are the cells (osteoblasts, osteocytes, osteoclasts) and the periosteum, a tough membrane that covers the bone and allows tendons and ligaments to attach to the bone.
Calcified cartilage is a type of cartilage that has undergone a process of mineralization, where calcium salts are deposited within its matrix. This transformation typically occurs in the transition zone between hyaline cartilage and bone, particularly during endochondral ossification in developing bones. The presence of calcified cartilage provides structural support and serves as a precursor to bone formation, playing a crucial role in skeletal development and growth. Unlike regular cartilage, calcified cartilage is less flexible and more rigid due to its mineral content.
Concentric lamellae
Concentric Lamellae -JSO
Calcified Tissue International was created in 1967.
Calcified fibroids are tumors that outgrow their own blood supple leading to degeneration.