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It is simply that among period 2 elements, oxygen (8) is one of the elements which has the largest number of isotopes, among period 4 elements, calcium (20) has the largest number of isotopes, and among period 5 elements, tin (50) has the largest number of isotopes. In fact tin has the largest number of isotopes overall.

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Q: What do you think nuclear chemists mean when they say that 8 20 and 50 are magic numbers for isotopes?
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