Rouleaux refers to the stacking of red blood cells (erythrocytes) in human blood. Rouleaux formation is enhanced in the presence of increased plasma proteins, leading to an increased erythrocyte sedimentation rate (ESR).
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Probably an incorrect spelling of "standard form".
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Autoagglutination should also be distinguished from "Rouleaux formation" wherein normal blood tends to form stacks on keeping, which disperses on dilution with normal saline.
When rouleaux formation is truly present, it is caused by an increase in cathodal proteins, such as immunoglobulins and fibrinogen.And the fibrinogen is not present in blood in vivo*This is not true. Fibrinogen is secreted by liver and is present in blood. The reason rouleaux do not form in vivo is that they only form under low shear stress conditions. With blood flow, the cross-sectional fluid velocity gradient in the blood vessel results in shear stress levels that exceed the threshold for rouleaux formation.
The red blood cells stack up like coins. http://en.wikipedia.org/wiki/Rouleaux
Anemic Hypoxia
Rouleaux formation occurs when red blood cells form rolls or stacks. If not due to an artifact, such as a result of not preparing the blood smear soon enough after placing the blood on the slide, it may be due to the presence of high concentrations of abnormal globulins or fibrinogen. This formation is found in multiple myeloma and macroglobulinemia.
it measn the RBCs are not whole
aplastic
We can not extract DNA from RBCs as they are without nucleus. only the source of DNA extraction is Leukocytes, RBCs are not good source of extraction but we can extract DNA from immature RBCs.
Multipotent hematopoietic stem cells------> Myeloid stem cells------>Reticulocytes----->RBCs
low rbcs count shows anaemia high rbcs count show polycythemia vera. rbcs enumerations shows the bonemarrow how much active.
Multiple Myeloma
rouleaux