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Rouleaux refers to the stacking of red blood cells (erythrocytes) in human blood. Rouleaux formation is enhanced in the presence of increased plasma proteins, leading to an increased erythrocyte sedimentation rate (ESR).

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What is the clinical significance of rouleaux formation?

Rouleaux formation, the stacking of red blood cells (RBCs) resembling a stack of coins, is clinically significant as it often indicates underlying inflammatory processes or increased plasma proteins, such as immunoglobulins or fibrinogen. This phenomenon can be associated with conditions like multiple myeloma, infections, and chronic inflammatory diseases. It may also affect blood viscosity and circulation, potentially leading to complications in affected patients. Therefore, recognizing rouleaux formation can aid in diagnosing and monitoring various medical conditions.


What causes rouleaux formation?

The red blood cells stack up like coins. http://en.wikipedia.org/wiki/Rouleaux


Why rouleaux formation does not occur in vivo?

When rouleaux formation is truly present, it is caused by an increase in cathodal proteins, such as immunoglobulins and fibrinogen.And the fibrinogen is not present in blood in vivo*This is not true. Fibrinogen is secreted by liver and is present in blood. The reason rouleaux do not form in vivo is that they only form under low shear stress conditions. With blood flow, the cross-sectional fluid velocity gradient in the blood vessel results in shear stress levels that exceed the threshold for rouleaux formation.


How is rouleaux formation differentiated from true agglutination?

Rouleaux formation is the stacking of red blood cells like a roll of coins, often seen in conditions like multiple myeloma. True agglutination is the clumping of red blood cells due to antibody-antigen interaction, such as in blood typing reactions. The key difference is that rouleaux formation involves cells stacking on top of each other, whereas true agglutination involves cells clumping together.


What is rouleaux formation?

Rouleaux formation occurs when red blood cells form rolls or stacks. If not due to an artifact, such as a result of not preparing the blood smear soon enough after placing the blood on the slide, it may be due to the presence of high concentrations of abnormal globulins or fibrinogen. This formation is found in multiple myeloma and macroglobulinemia.


What does lysed mean in respect of blood in urine trace lysed?

it measn the RBCs are not whole


Which form of hypoxia reflects poor O2 delivery resulting from too few RBCs or from RBCs that contain abnormal or too little hemoglobin?

Anemic hypoxia reflects poor oxygen delivery due to too few red blood cells (RBCs) or from RBCs that contain abnormal or too little hemoglobin. This leads to reduced oxygen-carrying capacity in the blood, resulting in inadequate oxygen reaching the body's tissues and cells.


What is the significance of Enumerated?

low rbcs count shows anaemia high rbcs count show polycythemia vera. rbcs enumerations shows the bonemarrow how much active.


What medical conditions are related to rouleaux formation of the red blood cells?

Multiple Myeloma


What is the French word for spring rolls?

Spring rolls are "des rouleaux de printemps".


Which blood condition is characterized by the abnormal stacking of erythrocytes like a pile of coins?

rouleaux


What is 'rouleaux' when translated from French to English?

"Rollers" about surf-waves, for hair, or in painting, "rolling pins" in pastry, and "rolls" of paper, scrolls, and wallpaper are English equivalents of the French word rouleaux. Whatever the meaning or use, the pronunciation remains "roo-lo" in French.