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Q: What is the process of x inactivation?
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What is the x chromosome inactivation?

this is the process by which one of the two copies of the X-chromosomes present in female animals is inactivated


Occurs when one x-chromosomes is randomly turned off and forms a barr body?

An X-inactivation occurs when one X-chromosome is randomly turned off and forms a Barr body. It is also known as lyonization.


What is x chromosome inactivation in human system?

its not inactive


What accounts for the mosaic color pattern of a female calico cat?

X chromosome inactivation


Is there a way to detect a carrier of autism?

Yes, testing the mother for skewed x-inactivation.


How is x inactivation an exception to Mendel's laws?

i really dont know but i have the same question and was hoping you could answer it


Which term describes something that happens in female mammals?

X chromosome inactivation happens in female mammals.


Why does x inactivation occurs in female not in male?

Male carry XY genotype whereas female has XX. Two copies of X chromosome means, there is a great chance of potentially toxic double dose of X-linked genes. It is known that 1000s of genes responsible for growth and cell viability are there in X chromosomes.To avoid the over production of these genes in female (where 2 X chromosomes present), there is a mechanism evolved that transcriptionally control or silence on of these two X chromosome.http://www.nature.com/scitable/topicpage/x-chromosome-x-inactivation-323


What is the difference between x-inactivation and genomic imprinting?

The difference between them is that : In genomic imprinting : one of the alleles in the two chromosomes ( for example the color of the eyes ) are tend to be heavily methylated, in contrast to the nonimpringting copy of the allele which typically is not methylated. In X-chromosome in activation : As you know in female there are two X chromosomes, so one of the two X xhromosomes is methylated which mean one of the two chromosomes become inactivation.


How do you reduce aggregation and inactivation by recombinant insulin?

aggregation and inactivation are some of the major problems hindering the prop[er production and expression of proteins. insulin can be artificially cheperoned to reduce aggregation and inactivation.- leninkandasamy@gmail.com


What is x linked inheritance diseases?

X-linked genes are found on the sex X chromosome. X-linked genes just like autosomal genes have both dominant and recessive types. Recessive X-linked disorders are rarely seen in females and usually only affect males. This is because males inherit their X chromosome and all X-linked genes will be inherited from the maternal side. Fathers only pass on their Y chromosome to their sons, so no X-linked traits will be inherited from father to son. Females express X-linked disorders when they are homozygous for the disorder and become carriers when they are heterozygous. An infamous recessive X-linked disorder is Hemophilia A. Hemophilia is a disorder where blood does not clot properly due to a shortage of clotting factor VIII. This disorder gained recognition as it traveled through royal families, notably the descendent's of Britain's Queen Victoria. X-linked dominant inheritance will show the same phenotype as a heterozygote and homozygote. Just like X-linked inheritance, there will be a lack of male-to-male inheritance, which makes it distinguishable from autosomal traits. One example of a X-linked trait is Coffin-Lowry syndrome, which is caused by a mutation in ribosomal protein gene. This mutation results in skeletal, craniofacial abnormalities, mental retardation, and short stature. X chromosomes in females undergo a process known as X inactivation. X inactivation is when one of the two X chromosomes in females is almost completely inactivated. It is important that this process occurs otherwise a woman would produce twice the amount of normal X chromosome proteins. The mechanism for X inactivation will occur during the embryonic stage. For people with disorders like trisomy X, where the genotype has three X chromosomes, X-inactivation will inactivate all X chromosomes until there is only one X chromosome active. X inactivation is not only limited to females, males with Klinefelter syndrome, who have an extra X chromosome, will also undergo X inactivation to have only one completely active X chromosome.


How might x inactivation cause patchy hairiness on women who have congenital generalized hypertrichosis even though the disease causing allele is dominant?

Since one X chromosome in each cell is randomly inactivated at some point during development, a woman heterozygous for hypertrichosis would have varying regions of patchy hair if the alleles responsible for the trait were located on the X chromosome. Variation would look similar to the varied tortoise shell coat color pattern on female cats, where the presence of yellow and black (red and gold/blue and cream) is controlled by X chromosome inactivation.