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X inactivation is a biological process that occurs in female mammals, where one of the two X chromosomes in each cell is randomly inactivated during early embryonic development. This ensures that females, like males, have one functional copy of the X chromosome, preventing an overdose of X-linked gene expression. The inactivated X chromosome condenses into a structure known as a Barr body and remains largely transcriptionally silent throughout the organism's life. This process is crucial for dosage compensation between the sexes.

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What is the x chromosome inactivation?

this is the process by which one of the two copies of the X-chromosomes present in female animals is inactivated


Occurs when one x-chromosomes is randomly turned off and forms a barr body?

X-chromosome inactivation is a normal process in female mammals where one of the two X chromosomes is randomly inactivated in each cell during embryonic development. The inactivated X chromosome forms a structure called a Barr body, which helps to equalize gene expression between males (XY) and females (XX). This process ensures that both males and females have a similar dosage of X-linked genes.


How is x inactivation an exception to Mendel's laws?

X inactivation is an exception to Mendel's laws because it involves the inactivation of one of the two X chromosomes in females, allowing for dosage compensation between males and females. This process results in the random silencing of one X chromosome and the formation of Barr bodies, altering the expected patterns of inheritance predicted by Mendel's laws.


Why is X-inactivation necessary in individuals with two X chromosomes?

X-inactivation is necessary in individuals with two X chromosomes to ensure that only one X chromosome is active in each cell. This process helps to balance gene expression between the two X chromosomes and prevent an imbalance of gene dosage, which could lead to developmental abnormalities and disorders.


What is x chromosome inactivation in human system?

its not inactive


Does x-inactivation happen in klinefelters syndrome?

X-inactivation typically occurs in individuals with Klinefelter syndrome, which is characterized by having an extra X chromosome (XXY). However, the extra X chromosome in Klinefelter syndrome may not undergo inactivation completely, leading to some cells expressing genes from the additional X chromosome. This can result in a variety of symptoms and characteristics associated with Klinefelter syndrome.


What is the difference between x-inactivation and genomic imprinting?

The difference between them is that : In genomic imprinting : one of the alleles in the two chromosomes ( for example the color of the eyes ) are tend to be heavily methylated, in contrast to the nonimpringting copy of the allele which typically is not methylated. In X-chromosome in activation : As you know in female there are two X chromosomes, so one of the two X xhromosomes is methylated which mean one of the two chromosomes become inactivation.


What accounts for the mosaic color pattern of a female calico cat?

X chromosome inactivation


Is there a way to detect a carrier of autism?

Yes, testing the mother for skewed x-inactivation.


Why does x inactivation occurs in female not in male?

Male carry XY genotype whereas female has XX. Two copies of X chromosome means, there is a great chance of potentially toxic double dose of X-linked genes. It is known that 1000s of genes responsible for growth and cell viability are there in X chromosomes.To avoid the over production of these genes in female (where 2 X chromosomes present), there is a mechanism evolved that transcriptionally control or silence on of these two X chromosome.http://www.nature.com/scitable/topicpage/x-chromosome-x-inactivation-323


How might x inactivation cause patchy hairiness on women who have congenital generalized hypertrichosis even though the disease causing allele is dominant?

Since one X chromosome in each cell is randomly inactivated at some point during development, a woman heterozygous for hypertrichosis would have varying regions of patchy hair if the alleles responsible for the trait were located on the X chromosome. Variation would look similar to the varied tortoise shell coat color pattern on female cats, where the presence of yellow and black (red and gold/blue and cream) is controlled by X chromosome inactivation.


What is bacterial inactivation?

Bacterial inactivation refers to the process of killing or rendering bacteria unable to grow or reproduce. This can be achieved through various methods such as heat treatment, chemical disinfection, or exposure to radiation. Bacterial inactivation is important in food preservation, water treatment, and medical settings to prevent the spread of infectious diseases.