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Which blood component is associated with Von Willenbrand disease?
von Willebrand disease results from inadequate von Willebrand factor. This problem is a blood clotting disorder.
What do platelets release?
Serotonin to continue the vasospasm.
What has the author Th Vukovich written?
Th Vukovich has written: 'The influence of human factor VIII/von Willebrand factor on human blood platelet aggregation' -- subject(s): Von Willebrand disease, Blood platelets, Aggregation
What is von Willebrand factor?
A protein found in the blood that is involved in the process of blood clotting.
Can a overdose of spanish fly cause Von Willebrand's Syndrome?
Von Willebrand's syndrome is a deficiency in the blood coagulation cascade. Specifically coag. factor 8. Coag factor 8 comes in 2 parts, von willebrand protein and another smaller glycoprotein. Heavy drinking may manifest some similar symptoms, but it's doubtful that it can be attributed to hemophilia related disease.
The endothelial cells of the blood vessel produce two important chemicals involved in hemostasis prostacyclin and?
von Willebrand factor
What is von willebrand?
The von Willebrand disease creates the tendency to bleed and bruise easily. It is an inherited clotting disorder that is usually less severe but more common. Those affected lack a plasma protein. Von Willebrand factor enables platelets to adhere to damaged blood vessel walls.
What is the medical name of the condition Von willebrand disease?
the body does not produce enough of a protein called von Willebrand factor(vWF) or produces abnormal vWF
Von Willebrand disease?
DefinitionVon Willebrand disease is the most common hereditary bleeding disorder.Causes, incidence, and risk factorsVon Willebrand disease is caused by a deficiency of von Willebrand factor. Von Willebrand factor helps blood platelets clump together and stick to the blood vessel wall, which is necessary for normal blood clotting. There are several types of Von Willebrand disease.Von Willebrand disease affects men and women equally. Most cases are mild. Bleeding may occur after surgery or when you have a tooth pulled. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) can make this condition worse. Bleeding may decrease during pregnancy.A family history of a bleeding disorder is the primary risk factor. In women with heavy or prolonged menstrual bleeding, von Willebrand is more common in Caucasian women than in African American women. The majority of women with heavy or prolonged menstrual bleeding do NOT have Von Willebrand disease.SymptomsAbnormal menstrual bleedingBleeding of the gumsBruisingNosebleedsSkin rashSigns and testsTests that may be done to diagnose this disease include:Bleeding time(is prolonged)Platelet aggregation testPlatelet count(may be low or normal)Ristocetin cofactor test (the primary assay test used to diagnose von Willebrand disease)Von Willebrand factor level (level is reduced)This disease may also alter the results of the following tests:Factor VIII levelVon Willebrand factor multimers (parts of the von Willebrand factor protein molecule)Von Willebrand disease may be hard to diagnose. Low von Willebrand factor levels and bleeding do not always mean you have von Willebrand disease.TreatmentMedications such as desamino-8-arginine vasopressin (DDAVP) can be given to raise the levels of von Willebrand factor, which will reduce the tendency toward bleeding.Some types of von Willebrand disease do not respond to DDAVP. Tests should be done to determine a patient's specific type of von Willebrand disease before trauma or surgery occurs. A trial of DDAVP can be done before surgery to test whether von Willebrand factor levels increase.The drug Alphanate (antihemophilic factor) is approved to decrease bleeding in patients with the disease who must have surgery or any other invasive procedure.Blood plasma or certain factor VIII preparations may also be used to decrease bleeding.Expectations (prognosis)Women who have this condition generally do NOT have excessive bleeding during childbirth.This disease is passed down through families. Therefore, genetic counseling may help prospective parents understand the risk to their children.ComplicationsBleeding (hemorrhaging) may occur after surgeries or other invasive procedures.If you have von Willebrand disease, do not take nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, without talking to your health care provider.Calling your health care providerCall your health care provider if bleeding occurs without reason.If you have von Willebrand disease and are scheduled for surgery or are in an accident, be sure you or your family notify the health care providers about your condition.ReferencesKessler CM. Hemorrhagic disorders: coagulation factor deficiencies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 180.
What is von Willebrand's disease?
The von Willebrand disease creates the tendency to bleed and bruise easily. It is an inherited clotting disorder that is usually less severe but more common. Those affected lack a plasma protein. Von Willebrand factor enables platelets to adhere to damaged blood vessel walls.
What are the chances of a woman having the gene for von Willebrand disease if her nephew has been diagnosed with the disease?
Von Willebrand disease may be hard to diagnose. Low Von Willebrand factor levels and bleeding do not always mean you have Von Willebrand disease. http://www.nlm.nih.gov/medlineplus/ency/article/000544.htm
What are the different clotting factors?
There are 13 clotting factors identified in blood that work together in the coagulation cascade to form blood clots. These factors include Factor I (fibrinogen), Factor II (prothrombin), Factor III (tissue factor), Factor IV (ionized calcium), Factors V, VII, VIII, IX, X, XI, XII, XIII, and von Willebrand Factor.
