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17 has two factors - 1 and 17.

17 - 1 = 16

if you want factors which are prime and not 1 and the number in question then ....

3 and 19 are different by 16 and they are the factors of 57.

And

13 and 29 are different by 16 and they are the factors of 377.

And

43 and 59 are different by 16 and they are factors of 2537.

And

73 and 89 .....

And

163 and 179 .....

There are numerous pairs of primes which differ by 16.

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16y ago

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