Well, there are 9 letters in Tennessee, and, based on the question, you can only use each letter once.
The first letter has 9 possible outcomes.
The second letter only has 8, because you have already used one.
The third would have 7, etc.
9 * 8 * 7 * 6 * 5 * 4 * 3 * 2 * 1 = 322,880
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In how many distinct ways can the letters of the word MEDDLES be arranged?
34,650
Tiffany
30 ways
180