0
pK1 = 2.3, pKr = 6, pK2 = 9.7 (all approximate)
at physiological pH, histidine has no net charge.
at pH 1, below all pKas and charge is +2
at pH 3, amine group proton pops off, so +1 charge
at pH 5, still below 6 and above 2.3 so +1 charge
if had pH above 6, for instance... at pH of 8 net charge is zero, or neutral... such that it is neutral at physiological pH (a bit above a pH of 7)
at pH 11, exceeds all pKas of amine, acid group, and R group. So net charge of -1
amine deprotonation, carboxylic acid deprotonation, and R group deprotonation happen pH 11 because it exceeds all pKs
Wiki User
∙ 13y ago
Add your answer:
Earn +20 pts
Alkalis have a pH what than 7?
great then 7
What is Ph in the formula for the surface area of a prism?
perpendicular height
Example of number relation problems?
how much of Ph 65lb seed does a dealer need to combine with 200lb of Ph45lb seed to make a Php 55lb blend?
How can you figure out the way to find the surface area for a triangular prism?
SA = 2B + Ph SA = 2(1/2ab) + (b + c + d)h SA = ab + (b + c + d)h
How many letters are there in the Welsh alphabet?
The Welsh alphabet is usually represented as 28 letters: a, b, c, ch, d, dd, e, f, ff, g, ng, h, i, l, ll, m, n, o, p, ph, r, rh, s, t, th, u, w, y The letter J can also be added as it is commonly used (as in the surname Jones).
The pI of a lysozyme is 11. What is the pH range in which the overall charge of the lysozyme is positive?
At pH values less than the pI point the net charge is positive. If at pH above the pI poiint, the charge will be negative.
What is the net charge of phosphatidylserine at pH 6.0?
- 1
What is the net charge of the dipeptide glu-lys at physiological pH?
Lys is basic and has a + charge, glu is acidic and - charged = net charge 0
At Ph 10 what charge would Zwitterion ion have?
it would depend on amino acid in question. pH above amino acid pI, zwitterion will carry net negative (-) charge. at pH below pI, zwitterion will carry net positive (+) charge. depending on the amino acid, some have more than one acidic or basic functional group. such functional groups can make the amino acid vary in net charge from 2- to 2+ if not more.
What charge does phenylalanine have at pH of 7.0?
Phenylalanine has a net 0 charge at pH 7.0 as the carboxy end has been deprotonated and the amino end still contains it's proton (hydrogen).
What is meant by isoelectric point of protein?
It is the pH at which a particular molecule or surface carries no net electrical charge
Is histidine aromatic?
The imidazole ring of histidine is aromatic at all pH values. It contains six pi electrons: four from two double bonds and two from a nitrogen lone pair.
How pH affect ionic bonding?
At low pH the over all net charge, for example amino acid residue ( which is connected by by ionic bonding) is going to be protonated which means there will be no ionic bonding at very low pH. As you raise the pH depending on the given pKas part of the residue starts to deprotonate which also could alter the net charge i.e the the ionic bonding is going to be affected.
Why histidine present frequently in an active site of enzyme?
The imidazole side chains and the relatively neutral pKa of histidine (ca 6.0) mean that relatively small shifts in cellular pH will change its charge. For this reason, this amino acid side chain finds its way into considerable use as a coordinating ligand in metalloproteins, and also as a catalytic site in certain enzymes
What is isoelectric pH?
it is the pH at which a particular molecule or surface carries no net electrical charge(or contain both electric charch, negative as wall as positive).
What is the pI of a protein?
pI is the isoelectric point. This is a pH value where a protein has no net charge. NOTE: Proteins may have multiple pI's.
What is the net charge of phosphatidylserine at pH 7?
DNA molecules are connected via a 5'-3' phosphodiester linkage to ribose molecules. The phosphate group within this linkage is contains a negatively charged oxygen atom at a PH of 7. This gives DNA its charge.
