The first Prime number after 50 is 53.
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There hasn't been a 1st Prime Minister of America, as America doesn't have one. The first President of America was George Washington, he was in office from April 30, 1789 to March 4, 1797. The Prime Minister is used in a parliamentary system. The first usage of the term was in 1625 when Cardinal Richelieu was named to head the royal council as prime minister to France.
11 Downing St is the home of the Chancellor of the Exchequer.
The prime factorization of 378 is 2 x 3 x 3 x 3 x 7 = 378
There are 100 members of the US Senate - two from each state (50 states).
More than one British Prime Minister did not have a wife. Four were never married. They were Ted Heath, Spencer Compton, William Pitt (the younger) and Arthur Balfour. A number of British Prime ministers were widowers during their term of office. Margaret Thatcher obviously did not have a wife.