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The second is 81 fewer than the first.
If you mean: 53 81 41 47 and 31 then 81 is a composite number while all the rest are prime numbers
The only prime numbers between 81 and 90 is... 83
The odd numbers between 40 and 53 are 41,43,45,47,49,51.
M6 - 81 = M6 - 92 = (M3 - 9)(M3 + 9) [difference of two squares]