4.
12x^2-64x-256=4(3x^2-16x-64)
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A single polynomial cannot have a greatest commonfactor. There is nothing that it will be in common with!
No.
It is not possible to give a sensible answer to this question. The greatest common factor (GCF) refers to a factor that is COMMON to two or more numbers or polynomials. If you have only one number or polynomial there is nothing for it to have a factor in common with!
16a2b4
5(x + 3)