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2-Iodobutane reacts faster than 2-chlorobutane in an Sn2 reaction due to the larger size of the iodine atom, which makes it a better leaving group. The larger iodine atom polarizes the C-I bond more easily, facilitating the departure of the leaving group and promoting the Sn2 reaction.

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Q: Why does 2-iodobutane react faster than 2-chlorobutane?
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