Well, no - but yes.
All numbers that people would come across in ordinary life can certainly be so expressed. As can all numbers that most scientists (other than mathematicians) are likely to come across in the context of their profession. So, in normal circumstances, the answer is no.
But, with some very, very large numbers even the scientific notation becomes cumbersome.
For example, googolplex is 10 to the power of 100100 so, in scientific notation it would be 10 raised to the power of 1 followed by 100100 zeros. And there are larger numbers.
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Scientific notation is used to show numbers raised to powers of ten. Pluto is a planet. Therefore, Pluto cannot be put into scientific notation because there are no numbers in Pluto to put to a power of ten...
You cannot. A number in scientific notation will be in its simplest form.
Numbers that cannot be expressed in the form of a ratio of two integers.
In general, you cannot. If the number in scientific notation has not been rounded then express it is normal form and proceed from there.
These are the numbers which cannot be expressed as ratios of two integers.