It depends on how high the jackpot is and how many people hit it. Theoretically, if the jackpot totals more than the cost of the ticket combinations, then you would make a profit as long as nobody else wins with you. This has actually been done before but is very risky since several people might share the jackpot.
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That is because whoever organizes the lottery - or another game of luck, for that matter - will calculate the probabilities so that they win - at least in the long term. As a result, if you pick every number combination, you would spend more than the total prizes.
The answer depends on which lottery and in which country/region.
9
There is only one combination since the order of the numbers in a combination does not matter.
every number from 0000 to 9999