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The greatest common factor of two or more prime numbers is 1.
25 is the greatest common factor. 5 is the greatest prime factor.
If the greatest common factor is 1, then the numbers are said to be co-prime or relatively prime.
Factor trees lead to prime factorizations. Negative numbers don't have prime factorizations. We'll do 98. If you want, you can put -1 in front of it. 98 49,2 7,7,2
73 is a prime number so 51,3x17 and 73 only have the number 1 as the greatest common factor.