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One way is to multiply through by the reciprocal of the term with the largest negative exponent.

eg if you have x-2 + 3x-1 + 5 = 0 then multiplying through by x2 will give

1 + 3x + 5x2 = 0, a standard quadratic.

But be careful about division by zero (or multiplication by 1/0 !!)

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Q: Help How do you simplify equations with negative exponents?
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