Starting in the middle of the room and working means you may have a fair bit of cutting one all the walls but a centered look is much better and likely allows you to use the pieces up.
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175
Assuming you mean 16x16 inches tiles... 441 tiles would cover the area exactly
297 16x16-inch tiles.
1.722 ceramic tiles
178 Tiles If the square footage is the actual room size you add 10% for wastee