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210 tiles
I will assume you mean that the tiles are 14 inches square and that the room is 18 ft by 33 ft. 18 ft is 216 inches, and 33 ft is 396 inches. As a first approximation, the room is 85536 sq inches so dividing this by 14 squared, or 196. we get just over 436.4 squares. However, this is unlikely to be enough with cutting to fit. It's usual to start in the centre of the room and to lay as many full tiles as possible, then to cut tiles to fill in the borders. You'd need about 140 full tiles, depending on exactly where you start. The number of part tiles needed will then depend on whether they have a nap or not. I'd say you need at least another 21 to be sure.
16 square tiles
If the floor tiles are measured in inches and the room is measured in feet then the tiles are 1sq feet and the room is 6x8 = 48 sq feet so you would need 48 tiles.
I assume you mean an 8ft x 6ft room, which is 48ft2. I assume you mean 12in x 12in tiles, which are 1ft2 tiles. I don't know how many tiles are in a box, but you would need 48 12in x 12in tiles.