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None of the zeros in that number are significant.
One of the rules of significant figures is that leading zeros are not significant; therefore, 0.00034 will only have TWO significant figures (3 and 4).
In the number 30.1, there are three significant figures. The digits 3, 0, and 1 are all considered significant because they contribute to the precision of the measurement. Zeros that are placeholders or trailing zeros after a decimal point are also considered significant in this case.
Five - any zeros after the decimal are significant unless they're placeholders. Any zeros between significant digits are significant.
There are 2 because of the leading zeros rule. Zeros at the beginning of a number are never significant.