There are 4 digits. You can pick one of them as the first digit. So you can pick the first number 4 ways. Having picked the first number, the second number you can pick in only 3 ways. Having picked the first number and the second number you can pick the third number in only 2 ways. Having picked the first number and the second number and the third number you can pick the fourth number in only 1 way.
So total ways of arranging 1468 would be 4 x 3 x 2 x 1 = 24
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24 ways
24
6 to the power of 6 so 6x6x6x6x6x6=46,656
you can arrange three beads 9 different ways.