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One hand is 4 inches, more or less. A hand is an old measure- the width of a hand - used mostly, I think, for measuring the height of horses. One could move up horse hand by hand and count how many hands tall the horse is.
To sign 'YES' make a fist with your hand and move it up and down, much the same as nodding your head. To say 'NO' it is the same, make a fist with your hand and shake side-to-side, like you are shaking your head.
Y takes a minute less.
It can be done by hand, but the explanation on how to do it takes up pages. It would be best to look in an inferential statistics book. It can be done much easier on a computer program called SPSS. This is a common program statisticians use.
it takes much time