According to Wikipedia, his main manuscript on calculus, which he called fluxions, was published in October, 1666. He was 2 months short of 24 years of age at the time.
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Calculus is around 350 years old. Newton developed it in his twenties. Which was in 1660.
Isaac newton was 26 yrs old when he became a professor of Maths. Isaac newton had a kidney Problem, that's he died. Isaac Newton died in Kensington, a place in England. Isaac Newton discovered gravity, by two apples, one falling on his head, the other ' he was sitting by the window when he saw, and apple drop down to the ground'.
Isaac was 60 years old (Genesis ch.25).
He started learning calculus when he was around twelve years old and had mastered it by the age of 15.
He was 60 years old (Genesis 25:26).