First off I would suggest googling khan academy subtracting. There are many wonderful videos and quizes.
Now 3605 - 4100 is -495. It is a negative number. I learned a system of lining the 3605 on top, the 4100 on the bottom and line them so that tens are lined up one under the other etc. I also learned a system of borrowing one from the ten value and when using it adding it as 10 to the units if I was asked to take a large figure from a smaller figure
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0.0025
8% of 4100 = 8% * 4100 = 0.08 * 4100 = 328
4100.00 minus 40 percent = 246040% off of 4100= 4100 - (40% * 4100 )= 4100 - (0.40 * 4100 )= 4100 - 1640= 2460
4100
75% of 4100 = 3075