No. Only larger numbers can be multiples of smaller number.
Ex: 48 is a multiple of 8.
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The least common multiple (LCM) of 3, 6, 8, and 16 is 48.
48
It is: 48
24 and 48
The answers are: -5*-3 = 15, -8*7 = -56 and -4*-12 = 48