you can use analyze <regression <probit
Less.
15 years old
LD50 or LC50 refers to the dose of a substance that is lethal to 50% of the test population. For phosphoric acid, the LD50 (oral, rat) is estimated to be around 1530 mg/kg. LC50 (inhalation, rat) is not readily available. As with any substance, caution should be taken when handling phosphoric acid due to its potential toxicity.
Poison is typically measured in terms of its toxicity, which is often described using units such as LD50 (lethal dose for 50% of the population) or LC50 (lethal concentration for 50% of a population). These measurements help determine the lethal dosage or concentration of a substance that can cause harm or death to living organisms.
Dimensions: 45.75" Wide, 25.75" Deep, 43" High (Rack Removed), 51.25" (Rack Installed), 222 lbs. With Bench
LC50 (lethal concentration 50%) is a standard measurement used in toxicology to determine the concentration of a substance that is lethal to 50% of the organisms exposed to it over a specified period of time. It is commonly used in studies to assess the toxicity of chemicals, pesticides, and other substances to various organisms. A lower LC50 value indicates a higher toxicity of the substance being tested.
The relationship between the degree of response of the organism and the quantity of the chemical always assumes a classic concentration-response form. the graphs represent the results of the tests in which groups of the organisms of the same species were exposed to various concentrations of a chemical for a specific length of time.
Toxicity is typically measured in terms of lethal dose (LD50), which represents the dose at which 50% of the test subjects exposed to a substance die. Other measures of toxicity include LC50 (lethal concentration) for gases and EC50 (effective concentration) for substances that don't necessarily cause death but have a measurable effect on an organism.
Hazard Class 6 contains poisonous materials (6.1) and infectious agents (6.2). Division 6.1: Poisonous material is a material, other than a gas, which is known to be so toxic to humans as to afford a hazard to health during transportation, or which, in the absence of adequate data on human toxicity:Is presumed to be toxic to humans because it falls within any one of the following categories when tested on laboratory animals (whenever possible, animal test data that has been reported in the chemical literature should be used):Oral Toxicity: A liquid with an LD50 for acute oral toxicity of not more than 500 mg/kg or a solid with an LD50 for acute oral toxicity of not more than 200 mg/kg.Dermal Toxicity. A material with an LD50 for acute dermal toxicity of not more than 1000 mg/kg.Inhalation Toxicity: A dust or mist with an LC50 for acute toxicity on inhalation of not more than 10 mg/L; or a material with a saturated vapor concentration in air at 20 °C (68 °F) of more than one-fifth of the LC50 for acute toxicity on inhalation of vapors and with an LC50 for acute toxicity on inhalation of vapors of not more than 5000 ml/m³; or
The relationship between the degree of response of the organisms and the quantity of the chemical always assumes a classic concentration-response form. The graphs represent the results of tests in which groups of the organisms of the same species were exposed to various concentrations of a chemical for a specific length of time. The least variability in the curve is at the 50% level of response. The concentration at which 50% level of the individuals react after a specified length of exposure is used as a measure of the activity or toxicity of the chemical agent. In determining the relative toxicity of a new chemical to aquatic organisms, an acute toxicity test is first conducted to estimate the median lethal concentration of the chemical in the water to which test organisms are exposed. LC50 is the concentration estimated to produce mortality in 50% of a test population over a specific time period.
YES they do. Its disgraceful.It depends on the test. Everyone complains about the Draize test, which is the one where they hold open rabbits' eyes and drip chemicals in them. The one that's worse is the LD50 test. This determines the "acute toxicity" of a substance--LD50 means the dose that kills half the animals who receive it. They can do a skin contact LD50, an oral LD50, an inhalation LD50 (more correctly LC50--inhaled chemicals are rated in parts per million in air) or an injection LD50. If you are doing an oral LD50 on antifreeze, you squirt a measured dose of antifreeze down the throats of 100 animals--anything from mice to dogs are used. You then count the number of animals that die over the next 14 days. At the end you euthanize the ones who are still alive. If 50 or more of the animals died from antifreeze, you record the dose as the LD50 and you're done. If fewer than 50 die, you repeat the test with a new batch of animals and a higher dose. Antifreeze kills by destroying the kidneys, and there are even worse chemicals than that--imagine having to run an inhalation LC50 on nerve gas!