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Cellular communication occurs through several modes, including autocrine, paracrine, endocrine, and juxtacrine signaling. Autocrine signaling involves a cell responding to substances it releases itself, while paracrine signaling involves communication between nearby cells through local signaling molecules. Endocrine signaling entails the release of hormones into the bloodstream, affecting distant target cells, and juxtacrine signaling requires direct contact between neighboring cells, often mediated by membrane-bound molecules. These modes enable cells to coordinate responses and maintain homeostasis in multicellular organisms.

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