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There are no two prime numbers in which a product of 100 is possible.
Each of the 25 prime numbers from 1 to 100 has exactly two factors, 1 and the number itself. The other 75 numbers from 1 to 100 are not prime numbers because none of them have exactly two factors.
Numbers with more than two factors are not prime numbers
An example of two numbers which add together to make 100 are 47 and 53.
The prime numbers less than 100 that contain an 8 are 83 and 89. So, there are two prime numbers that are less than 100 and contain an 8.