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1-7-21-46-85-141. Take the "first differences" between the numbers.
6, 14, 25, 39, 56. Take the SECOND differences.
8, 11, 14, 17. Ah. It looks like a sequence where the second difference is two.
Continue the next number in the second difference list. It would be 17 + 3 = 20. Add that number to the last number in the first difference list. 56 + 20 = 76. And that's what you add to the last number in the original pattern to get the next number in it.
141 + 76 = 217.
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