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Jesus and his twelve deciples.
The number twelve signifies a divine organizational arrangement. For example, there were 12 tribes of Israel and 12 apostles. In each case, the arrangement was instituted by God.
The span of a life. In the days that this was coined that was considered to be seventy years. Threescore used to be used for sixty, in the way that we still use a dozen for twelve, and (occasionally) score for twenty.
Number of extra items
In the Bible, the number twelve often symbolizes completeness or perfection. It is associated with the twelve tribes of Israel in the Old Testament and the twelve apostles of Jesus in the New Testament. The number twelve is significant for representing God's chosen people and the foundation of his work in the world.