multiply it by 2
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It does not mean anything at all. "Twice a number" is only one number while "the difference" must refer to two numbers, not just one.
The question cannot be answered because it is ambiguous. Does "twice the sum of 16 and a number" mean "2*16 + x" or does it mean "2*(16 + x)"
2 (N + 3)
This means that X=2N-3.
If you mean: 5, 10, 20, 40 then the following number is twice the previous number which will be 80