"Trend" is something like tendency, and "upward" means that something is increasing. There is a general tendency that whatever is being considered, increases over time.
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The direction in which the trend analysis points.
One example of a 'Trend' would be; In a Graph if there is a point in the graph where you start to see a pattern, its sort of like a trend. But usually you have to explain it, you would have to understand all of the data to know what the actual trend is.
Dose is a measured portion of a medicine. Therefore a dose trend means the pattern of dosage of medication over a period of time.
A trend is like a pattern except not as precise
trend line