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The substantia nigra is a crucial part of the brain located in the midbrain, primarily involved in the regulation of movement. It contains dopaminergic neurons that project to the striatum, playing a key role in the coordination and smooth execution of voluntary motor activities. Dysfunction or degeneration of these neurons is associated with movement disorders, most notably Parkinson's disease, leading to symptoms such as tremors, rigidity, and bradykinesia. Additionally, the substantia nigra is involved in reward processing and the regulation of mood.

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3w ago

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What happens when the substantia nigra is damaged?

Degeneration of neurons especially in substantia nigra of both sides might cause Parkinson's disease.


What does Eldepryl do?

It may slow degeneration of the substantia nigra


The brain structure that produces dopamine?

substantia nigra


What is black substance also known as?

substantia nigra


What is substantia nigra also known as?

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Where is substantia nigra located?

The substantia nigra are located in an area of the brain around the lateral ventricles known as the basal ganglia. This is an addition to the above-mentioned answer. To be more specific, substantia nigra lies in the midbrain, dorsal to the cerebral peduncles.


What is the Substantia nigra?

One of the movement control centers of the brain


What is dopamine secreted by?

Dopamine is primarily secreted by nerve cells in the brain, specifically by cells in the substantia nigra and ventral tegmental area. It plays a role in various brain functions such as regulating mood, motivation, and movement.


What is the relation between substantia nigra and alzheimer's disease?

The substantia nigra is best known for its production of dopamine, a major neurotransimitter used in certain cell populations in the brain. The most common link with respects to pathology, is in Parkinson's disease, where these cell populations (in the substantia nigra) die off, and the brain has very low amounts of dopamine to work with. Sorry I couldn't be more specific to the alzheimer's respects, but I'm just giving what I know. Take care.


Does Parkinson's disease affect the brain stem?

No, parkinson's affects the dopaminergic neurons of the substantia nigra, which is part of the mid-brain.


What has the author P H M F van Domburg written?

P. H. M. F. van Domburg has written: 'The human substantia nigra and ventral tegmental area' -- subject(s): Aging, Anatomy & histology, Basal Ganglia Diseases, Mesencephalic tegmentum, Pathology, Substantia Nigra, Tegmentum Mesencepahli


Which part of the brain produces dopamine?

Dopamine is produced in the substantia nigra and ventral tegmental area, which are located in the midbrain. These areas are part of the brain's reward system and are involved in regulating movement and motivation.