Activated Partial Thromboplastin Time (APTT) is a blood test that measures the time it takes for blood to clot, specifically assessing the intrinsic and common coagulation pathways. It is significant in diagnosing bleeding disorders, monitoring anticoagulant therapy (such as heparin), and evaluating the functionality of clotting factors. Abnormal APTT results can indicate conditions such as hemophilia or the presence of lupus anticoagulants, which may increase the risk of bleeding or thrombosis.
An aPTT (activated Partial Thromboplastin Time) sample should be collected in a blue-top tube, which contains sodium citrate as an anticoagulant. The blue-top tube typically has a 3.2% concentration of sodium citrate, which helps preserve the sample for accurate testing. It's important to maintain the proper blood-to-citrate ratio for reliable results.
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Therapeutic range for aPTT is 45-75 seconds.
A blue-top tube (citrate tube) is used for collecting blood samples for the activated partial thromboplastin time (APTT) test.
The color of the tube commonly used for APTT (Activated Partial Thromboplastin Time) is light blue.
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A low APTT result may suggest a bleeding disorder caused by factors like deficiencies in clotting factors (such as hemophilia) or the presence of inhibitors to clotting factors. Further evaluation is necessary to determine the specific cause of the prolonged APTT.
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The normal range for activated partial thromboplastin time (APTT) is typically between 25-35 seconds. However, it can vary slightly depending on the laboratory's specific reference range. Outside of this range may indicate a bleeding disorder or a clotting factor deficiency.
APTT, or Activated Partial Thromboplastin Time, is a blood test that measures the time it takes for blood to clot. It assesses the intrinsic and common pathways of coagulation, helping to evaluate bleeding disorders, the effectiveness of anticoagulant therapy, and the function of various clotting factors. A prolonged APTT can indicate issues such as hemophilia, liver disease, or the presence of anticoagulants. This test is commonly used in clinical settings to monitor patients on heparin therapy or to investigate unexplained bleeding.