A trend can mean the decreasing value of a function of time, i.e. f(t+dt) - f(t) < 0.
It can also mean a negative slope, i.e., df/dt < 0.
It may come up in statistics, economics (Stock Market) or Biology (population size) but could be used anywhere.
Sometimes a trend line is some kind of average taken over a time window. It could be the maximal decrease of local maxima, or it could be the average decline over a window of time.
<Feb 18, 2014 - B.C.>
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It is usually a linear measure in the downward direction.
A trend is like a pattern except not as precise
One example of a 'Trend' would be; In a Graph if there is a point in the graph where you start to see a pattern, its sort of like a trend. But usually you have to explain it, you would have to understand all of the data to know what the actual trend is.
Dose is a measured portion of a medicine. Therefore a dose trend means the pattern of dosage of medication over a period of time.
Usually it refers to the straight line regression of a variable against time.