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A high volume of distribution (Vd) indicates that a drug extensively distributes throughout the body's tissues and compartments, rather than remaining confined to the bloodstream. This suggests that the drug may have a high affinity for tissues or can permeate cell membranes easily. A high Vd often correlates with a longer duration of action and may require higher doses for effective therapeutic levels in the plasma. It can also imply that the drug is less likely to be effectively cleared by the kidneys or liver.
What else can I help you with?
Why volume of distribution is also called apparent volume of distribution?
The volume of distribution (Vd) is often referred to as the "apparent volume of distribution" because it does not represent a true physical volume within the body. Instead, it is a theoretical volume that describes how extensively a drug disperses throughout body fluids and tissues relative to its concentration in the blood. This term emphasizes that Vd is derived from pharmacokinetic calculations rather than direct measurements, reflecting the drug's distribution characteristics rather than its actual distribution in physical space.
If the mean of a normal distribution i s105 what is the median of the distribution?
In a normal distribution, the mean, median, and mode are all equal. Therefore, if the mean of the distribution is 105, the median of the distribution is also 105. This property holds true for any normal distribution regardless of its standard deviation.
Which distribution function has equal mean and variance?
The exponential distribution and the Poisson distribution.
The mean of a standard normal distribution is?
The mean of a standard normal distribution is 0.
If the mean of a distribution is 105 what is the median of the distribution?
The relationship between the mean and the median depends on the shape of the distribution. In a symmetric distribution, the mean and median are equal, so if the mean is 105, the median would also be 105. However, if the distribution is skewed, the median could be less than or greater than the mean. Without additional information about the distribution's shape, we cannot definitively determine the median.
What are the differences in drug distribution within the body when comparing a high volume of distribution to a low volume of distribution?
When comparing a high volume of distribution to a low volume of distribution, the main difference lies in how widely the drug spreads throughout the body. A high volume of distribution means the drug is extensively distributed in tissues beyond the blood, while a low volume of distribution indicates that the drug stays primarily in the bloodstream. This can affect the drug's concentration in different body compartments and its overall effectiveness.
RDW-CV was high - what does this mean?
RDW-CV stands for Red Cell Distribution Width - Cell Volume. It means that the red blood cells vary a lot in size.
Difference between Apparent volume distribution and volume distribution?
The volume distribution is the theoretical volume into which (for example a drug) is distributed into the body. The apparent volume is the volume into which the drug is KNOWN to distribute in the body.
What does high red cell distribution mean?
Question does not make sense to a biologist!
What does the medical abbreviation RDWCV mean?
Red cell distribution width (RDW) and mean corpuscular volume (MCV) to help determine the causes of anemia.
Low mch and high rdw?
Low Mean Corpuscular Hemoglobin High Red cell distribution width.
Why volume of distribution is also called apparent volume of distribution?
The volume of distribution (Vd) is often referred to as the "apparent volume of distribution" because it does not represent a true physical volume within the body. Instead, it is a theoretical volume that describes how extensively a drug disperses throughout body fluids and tissues relative to its concentration in the blood. This term emphasizes that Vd is derived from pharmacokinetic calculations rather than direct measurements, reflecting the drug's distribution characteristics rather than its actual distribution in physical space.
What is the mean of the sampling distribution equal to?
The mean of the sampling distribution is the population mean.
The mean of a distribution of scores is the?
The mean of a distribution of scores is the average.
What kind of products are provided by DePaul Distribution Services for educational purposes?
DePaul Distribution Services provides its customers with a number of products that can be used for educational purposes. For example, the company offers high volume copying and digital scales.
What does the medical abbreviation RDW mean?
Red Cell Distribution WidthRDW = Red cell Distribution Width. A measure in variation of the sizes of the Erythocytes (red blood cells)RDW stands for red cell distribution width. It is a measure of the variability of the size (volume) of red cells. Red cells of uniform size--no matter what that size is--will have a low RDW. A population of cells which vary greatly in size will have a high RDW. Another name for variability in red cell size is anisocytosis. In both thallasemia and iron deficiency anemia, the average cell size (measured as MCV, mean corpuscular volume) is low. But in iron deficiency anemia, unlike thallasemia, the RDW is increased.Red Cell Distribution Width in PercentageRed-Blood Cell Distribution Width
What does it mean if someone has a high stoke volume?
They are easily excitable which can lead to wet pants.
