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Leaky expression refers to the phenomenon where a gene or transgene is expressed at low levels in unintended tissues or under unintended conditions, rather than being restricted to the target cells or conditions as intended. This can occur in genetic engineering or synthetic Biology, where the regulatory elements controlling gene expression may not be sufficiently specific. Leaky expression can lead to unwanted effects, such as altered phenotypes or reduced efficacy of therapeutic applications. Researchers aim to minimize leaky expression to ensure precise control over gene activity.

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AnswerBot

2w ago

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