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In chemistry, conformational isomerism is a form of stereoisomerism in which the isomers can be interconverted exclusively by rotations about formally single bonds.

conformational space needs to be found for different purposes like docking, annealing, to test proteins etc

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Q: What is meant by conformational space?
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What is the difference between constitutional isomers and conformational isomers in organic chemistry?

Constitutional isomers have different molecular structures, while conformational isomers have the same structure but differ in the arrangement of atoms in space.


What is conformational its something to do with isomers in chemistry but do know what?

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Is conformational isomerism restricted only to carbon compounds?

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A conformational change refers to the alteration in the shape or structure of a molecule, typically a protein, due to internal or external factors like binding of ligands or changes in environment. These changes can affect the function or activity of the molecule.


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Which molecule is the conformational diastereomer to the molecule at the top?

The molecule that is the conformational diastereomer to the molecule at the top is the one that has a different spatial arrangement of atoms due to rotation around single bonds.


What is the difference between conformational isomers and stereoisomers?

Conformational isomers differ in the rotation around single bonds, while stereoisomers have the same connectivity but differ in the spatial arrangement of atoms.


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How do gauche butane interactions influence the conformational preferences of cyclohexane?

Gauche butane interactions affect the conformational preferences of cyclohexane by creating steric hindrance that can stabilize or destabilize certain conformations.


What is the conformational analysis of 3-methylpentane in a Newman projection?

Conformational analysis of 3-methylpentane in a Newman projection involves studying the different possible arrangements of its atoms to understand its stability and energy.


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