With a suitable choice of the generating rule, any number of your choice can be next.
A simple polynomial, though is
Un = (n3 - 8n2 + 11n + 36)/2 for n = 1, 2, 3, etc which gives the next number in the sequence as another 8.
10
49
485
The next number is 485.
The sequence appears to be decreasing by 2, then increasing by 5, and then decreasing by 2 again. Following this pattern, after 19, the next number would follow the same decrease of 2. Therefore, the next number in the sequence is 17.
17?
The next number in the sequence is 27.
It is 5n+2 and so the next number is 22
44
Think it's 30...then 20
It is 129.
The pattern appears to be: subtract 6, add 17, subtract 14, add 9, subtract 7. Following this pattern, the next number should be obtained by adding 3 to the last number in the sequence, which is 6. Therefore, the next number in the sequence is 9.
49
10
333
55
485