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AnswerSome say the significance was that there were traditionally twelve tribes of Israel Some say the significance was that there are twelve constellations in the zodiac. Some say both, one leading to the other.
It means completeness in an organizational setting. the twelve apostles, the twelve tribes of Israel, and so forth.
The twelve times table consists of the products of 12 and each number from 1-12 (and to infinity):1x12 = 122x12 = 243x12 = 364x12 = 485x12 = 606x12 = 727x12 = 848x12 = 969x12 = 10810x12 = 12011x12 = 13212x12 = 144...etc.
They are important as they went all over the world to tell about Christ Peter went to Rome and Thomas came to Kerala in India.
Twelve is twelve, PERIOD